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Accurate Fluorescein Optical pH Sensing of Biofilms on Teeth and Food

This technology offers accurate optical pH sensing for biofilms using multiple wavelength emissions for data processing. This system can prevent tooth and gum disease before it occurs and produce proper patient care.
Technology No. BDP 8684
What is the Problem?

Biofilm formation is a major problem in oral healthcare, food processing environments and on surgical instruments in a medical environment. Oral biofilms may be a medium that enables tooth decay or the tooth decay process of acidification and enamel demineralization. It is known that pH measurements can indicate the risk of biofilm formation and thus tooth decay in patients. However, technologies for examining and measuring this oral biofilm in early disease stages do not exist, leading to biofilm formation and growth.

What is the Solution?

The solution is a system and method for accurate optical pH sensing of biofilms. The pH level is measured using multiple wavelengths emitted by a fluorescent substance (fluorescein). This device emits an excitation light, which collects emitted light and processes the data. This can be done in normal lighting conditions at a dentist’s clinic.

What Differentiates it from Solutions Available Today?

Existing solutions rely on treating the cavities once they form, instead of preventing them before they occur. Preventing tooth and gum disease before they occur would increase the quality of care and the patient outcomes and provides a differentiating service for a care provider. Care could move towards prevention instead of treatment.

Patent Information:

WO2020018946A1

  • swap_vertical_circlemode_editAuthors (1)
    Eric Seibel
  • swap_vertical_circlelibrary_booksReferences (1)
    1. Manuja Sharma, Lauren K. Lee, Matthew D. Carson, David S. Park, Se W. An, Micah G. Bovenkamp, Jess J. Cayetano, Ian A. Berude, Leonard Y. Nelson, Zheng Xu, Alireza Sadr, Shwetak N. Patel, and Eric J. Seibel (44774), O-pH: Optical pH Monitor to Measure Dental Biofilm Acidity and Assist in Enamel Health Monitoring, Trans Biomed Engineering
  • swap_vertical_circlecloud_downloadSupporting documents (1)
    Product brochure
    Accurate Fluorescein Optical pH Sensing of Biofilms on Teeth and Food.pdf
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