Cystic Fibrosis Respiratory Symptom Diary (CFRSD) and Chronic Respiratory Infection Symptom Score (CRISS)

The Cystic Fibrosis Respiratory Symptom Diary CFRSD quantifies cystic‐fibrosis disease burden over the preceding 24 hours through eight core respiratory items:  difficulty breathing, cough, sputum production, chest tightness, wheeze, feverishness, fatigue, and chills/sweats.  This instrument captures symptom severity at baseline, during medically treated exacerbations, and throughout recovery. It further assesses quality-of-life impacts: emotional effects (frustration, sadness/depression, irritability, worry, and sleep disturbance) and activity limitations (time spent sedentary, reduction in usual activities, and missed school or work). Together, these measures provide a comprehensive, patient-centered profile suitable for use in clinical trials and routine monitoring.   

The CFRSD is available in multiple languages:  English (U.S.), English (U.K.), French (France), German (Germany), German (Switzerland), Spanish (Spain), Arabic (Israel), Danish (Denmark), Dutch (Netherlands), Hebrew (Israel), Italian (Italy), Russian (Israel), Swedish (Sweden)

Authors:  Goss C, Patrick DL, and Marshall B
Co-Authors:  Edwards T and Caldwell E
Copyright:  University of Washington
Purpose:  Research & Intervention
Pathology:  Chronic Respiratory Infection
Disease/Condition:  Cystic Fibrosis
Population:  Adults, 18 and older
Type of Instrument:  Symptoms
Mode of Administration:  Self-administered
Time recall:  Daily
Number of Items: 16

For the validation reference please see below.