3D Printable Hydrogel Materials
This technology offers a series of hydrogel compositions that are responsive to temperature, applied pressure, and chemical crosslinking. The hydrogel does not degrade in water and is consistent in production and mechanical properties for specific applications.
A PDMS-Acrylate Resin for Stereolithographic 3D-Printing of PDMS
This technology offers an automated 3D fabrication of PDMS-acrylate resin for custom microfluidics. This development could be used for high-throughput and autonomous microfluidics, soft-robotics, point-of-care diagnostics, implantable microdevices, tissue engineering and organ-on-a-chip systems.
BSA-Based Resin for Vat Photopolymerization
This technology offers a bovine serum albumin-based resin for stereolithographic apparatus 3D printing. This method affords bioplastic objects with shape-memory behavior and enables superior mechanical performance.
DNA Repair through Nanotherapeutic Delivery of NAD+ Precursors
When brain cell DNA is damaged by disease, the cell's attempts to repair the DNA can dry up crucial resources needed to maintain the cell's energy, eventually leading to cell death. This technology aims to replenish these resources by using cost-effective, highly customizable nanopeptoids to deliver building blocks for the needed resources and achieve the first effective method for targeted energy regeneration in the brain. This both aids the repair of DNA and helps to prevent cell death.
Energy-Efficient Fusion Bonding with RF Heating
Polymers and composites are crucial materials for automotive and aerospace manufacturing but require new methods to weld them to other materials. Through the use of RF heating, energy can be efficiently targeted to heat up the desired weld. The technology uses a closed-loop system with high automation, controlling the heating power through onboard sensor data for consistent welds.
Extendable Flex Shaft
This technology offers a flexible, extendable torque transmission device that is easily fabricated and reduces the mechanical complexity of the current approaches. The system gains its mechanical properties by wrapping a repeated geometric tiling to create a hollow cylinder.
Globular Protein Preparation and Deposition as a 3D Printing Substrate
Advancements in tissue engineering and bioprinting are challenged by the lack of available materials to improve hydrogel developments. The incorporation of affordable and naturally sourced tannic acid (TA) in hydrogels can tune the swelling behavior and mechanical properties for 3D printing.
Hydrogel Tubes and Coaxial Fibers from Custom 3D Printed Nozzles
This technology offers a fabrication process for coaxial fibers and hollow tubes with hydrogel compositions. Custom nozzles extrude and cure the hydrogel during the printing process and shows potential in in vitro models.
Injectable Recombinant Protein-Based Hydrogels for Therapeutic Delivery
The solution is a self-healing protein-based hydrogel that supports minimally invasive cell delivery through catheter injection.
Microbial Consortia Immobilized Bioreactors
This technology offers a 3D printed hydrogel with two different cell populations embedded. This process can enable large scale production with a tunable approach for co-culture bioprocess applications.
Photopatterned Biomolecule Immobilization to Guide 3D Cell Fate in Natural Protein-Based Hydrogels
The technology is a method using photomediated oxime ligation to covalently decorate naturally derived hydrogels with bioactive proteins, such as growth factors, to spatially control encapsulated cell fate.
Photopatterning of Hydrogel Biomaterials
The solution is a generalizable and intuitive strategy using lasers to print 3D non-discrete patterns across cellular scales in biomaterials.
Printed Energy Harvesting Wearables
This technology utilizes composite materials as the fabric additive to enable the development of stretchable high-performance thermoelectric power generators. The durability of the wearable device is improved by undergoing 15,000 stretching cycles without mechanical or electrical failure.
Protein-Based Resins for Additive Manufacturing
This technology is a methacrylated bovine serum albumin resin for 3D printed structure that are biocompatible and patterned by light. It can be used for hydrogel resins because it is simple to prepare and biodegradable.
Reinvigorated Cyclic Ruthenium Initiators for Enhanced Ring-Expansion Metathesis Polymerization
This technology offers a tethered ruthenium-based initiator for common linear polymerizations. This system improves polymerization kinetics for initiator stability and enables more versatility.
Reprogrammable Metasurfaces
This technology offers reprogrammable metasurfaces for tailoring mechanical material properties. This system is rapid and repeatable to fit new applications, eliminating redesign.
SpyLigation: Spatiotemporal Control of Protein Function
The innovation is a method to activate protein function near-instantaneously and irreversibly in response to light, accomplished through genetically encoded triggered protein-protein ligation reactions. This method, known as light-activated SpyLigation (LASL), stably re-assembles bioactive proteins from non-functional split fragment pairs following brief exposure to light.
Surface-Passivated Silicon Quantum Dot Phosphors
This technology offers a synthesis of brightly fluorescent colloidal silicon quantum dots that are low cost and produced at a large-scale compared to conventional methods that are high cost and toxic from heavy metal ingredients. The method involves electrochemical etching of 6-inch silicon wafers to produce silicon nanoparticles that are a heavy-metal-free composition, chemical stability and abundant in starting materials.