DNA Repair in the Brain through Targeted Nanoparticle Delivery of NAD+ Precursors
When brain cell DNA is damaged by disease, the cell's attempts to repair the DNA can dry up crucial resources needed to maintain the cell's energy, eventually leading to cell death. This technology aims to replenish these resources by using cost-effective, highly customizable nanopeptoids to deliver building blocks for the needed resources and achieve the first effective method for targeted energy regeneration in the brain. This both aids the repair of DNA and helps to prevent cell death.
Injectable Recombinant Protein-Based Hydrogels for Therapeutic Delivery
The solution is a self-healing protein-based hydrogel that supports minimally invasive cell delivery through catheter injection.
Photopatterning of Hydrogel Biomaterials
The solution is a generalizable and intuitive strategy using lasers to print 3D non-discrete patterns across cellular scales in biomaterials.
Surface-Passivated Silicon Quantum Dot Phosphors
This technology offers a synthesis of brightly fluorescent colloidal silicon quantum dots that are low cost and produced at a large-scale compared to conventional methods that are high cost and toxic from heavy metal ingredients. The method involves electrochemical etching of 6-inch silicon wafers to produce silicon nanoparticles that are a heavy-metal-free composition, chemical stability and abundant in starting materials.
Two-Component Co-Assembling Two-Dimensional Protein Structures
This technology involves the creation of two-dimensional protein structures using two distinct polypeptides that form rigid interfaces, offering enhanced control and functionality.