Method for Quantification of Lipoprotein(a)
The innovation offers a reference method for the quantification of lipoprotein(a) in clinical and research applications and serves to broaden the use of Lp(a) as a biomarker in cardiovascular disease outcome measurement and risk assessment.
TBD
Targeting von Willebrand Factor to Model Disease in Human Pluripotent Stem Cells
The disclosed technology offers a CRISPR-Cas9 generated, isogenic hPSC-EC in-vitro model for studying disease dynamics and therapeutic candidates for VWF-deficient diseases such as Von Willebrand disease (VWD).
TBD
Treating Mitochondrial Dysfunction in Heart Failure
This technology targets the root cause of heart failure by employing nicotinamide riboside (NR) to protect mitochondrial function and reduce inflammation, and normalizing MRPP2 levels to improve mitochondrial DNA processing, offering a potential avenue to reverse the course of heart failure.
TBD