3D Printable Hydrogel Materials
This technology offers a series of hydrogel compositions that are responsive to temperature, applied pressure, and chemical crosslinking. The hydrogel does not degrade in water and is consistent in production and mechanical properties for specific applications.
A PDMS-Acrylate Resin for Stereolithographic 3D-Printing of PDMS
This technology offers an automated 3D fabrication of PDMS-acrylate resin for custom microfluidics. This development could be used for high-throughput and autonomous microfluidics, soft-robotics, point-of-care diagnostics, implantable microdevices, tissue engineering and organ-on-a-chip systems.
Extendable Flex Shaft
This technology offers a flexible, extendable torque transmission device that is easily fabricated and reduces the mechanical complexity of the current approaches. The system gains its mechanical properties by wrapping a repeated geometric tiling to create a hollow cylinder.
Photopatterned Biomolecule Immobilization to Guide 3D Cell Fate in Natural Protein-Based Hydrogels
The technology is a method using photomediated oxime ligation to covalently decorate naturally derived hydrogels with bioactive proteins, such as growth factors, to spatially control encapsulated cell fate.
Reinvigorated Cyclic Ruthenium Initiators for Enhanced Ring-Expansion Metathesis Polymerization
This technology offers a tethered ruthenium-based initiator for common linear polymerizations. This system improves polymerization kinetics for initiator stability and enables more versatility.
Reprogrammable Metasurfaces
This technology offers reprogrammable metasurfaces for tailoring mechanical material properties. This system is rapid and repeatable to fit new applications, eliminating redesign.
SpyLigation: Spatiotemporal Control of Protein Function
The innovation is a method to activate protein function near-instantaneously and irreversibly in response to light, accomplished through genetically encoded triggered protein-protein ligation reactions. This method, known as light-activated SpyLigation (LASL), stably re-assembles bioactive proteins from non-functional split fragment pairs following brief exposure to light.
Two-Component Co-Assembling Two-Dimensional Protein Structures
This technology involves the creation of two-dimensional protein structures using two distinct polypeptides that form rigid interfaces, offering enhanced control and functionality.